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Premenstrual Syndrome (PMS) and Premenstrual Dysphoric Disorder (PMDD)

Premenstrual syndrome (PMS) refers to a group of physical, emotional and behavioural symptoms that occur in the days before a period and usually improve once menstruation begins. Premenstrual dysphoric disorder (PMDD) is a more severe form of PMS that can have a significant impact on mood, relationships, work and daily life.

Commonality

PMS is very common and affects up to 75% of women of reproductive age.


PMDD is less common, affecting approximately 3–8% of women, but symptoms are often much more severe and disruptive.

Causes

The exact cause of PMS and PMDD is not fully understood, but they are thought to result from increased sensitivity to normal hormonal changes during the menstrual cycle.


Possible contributing factors include:

  • Fluctuations in oestrogen and progesterone after ovulation

  • Changes in brain neurotransmitters such as serotonin and GABA

  • Genetic predisposition

  • Stress or previous trauma

  • Underlying mental health conditions


For women with PMDD, the brain appears to react differently to normal hormonal changes.

Symptoms

Symptoms usually occur during the 7–14 days before a period and improve once menstruation begins.


Emotional and behavioural symptoms may include:

  • Mood swings

  • Irritability or anger

  • Anxiety

  • Low mood

  • Difficulty concentrating

  • Tearfulness or emotional sensitivity


Physical symptoms may include:

  • Bloating

  • Breast tenderness

  • Headaches

  • Fatigue

  • Sleep disturbance

  • Changes in appetite

  • Cramps or back pain


PMDD may cause more severe symptoms, including:

  • Intense mood swings

  • Severe irritability or anger

  • Anxiety or panic attacks

  • Depression or feelings of hopelessness

  • Loss of interest in daily activities

  • Emotional outbursts


In severe cases, PMDD may be associated with suicidal thoughts, which require urgent medical support.

Effects on Fertility

Diagnosis

Diagnosis is based on a detailed assessment of symptoms and their relationship to the menstrual cycle.


Assessment may include:

  • Detailed menstrual and symptom history

  • Review of physical and mental health

  • Evaluation of symptom timing throughout the cycle

  • Exclusion of other conditions such as thyroid disorders or depression

  • Symptom tracking using a diary or menstrual tracking app


Recording symptoms over two or more menstrual cycles can help confirm the diagnosis.


Because PMDD symptoms can resemble anxiety or depressive disorders, accurate diagnosis is essential.

Treatments

Treatment depends on symptom severity and how much symptoms affect daily life.


Lifestyle measures may include:

  • Regular physical activity

  • Balanced diet

  • Reducing caffeine and sugar intake

  • Adequate sleep

  • Stress management techniques such as mindfulness or yoga


Medical treatments may include:

  • Hormonal contraception to suppress ovulation

  • Oestrogen therapy with appropriate progesterone protection

  • Selective serotonin reuptake inhibitors (SSRIs)

  • Pain relief for headaches or pelvic discomfort


Psychological support may include:

  • Cognitive behavioural therapy (CBT)


In rare, severe cases, additional hormonal therapies or surgical options may be considered.

Ongoing Care

Living with the Condition

PMS and PMDD can affect many aspects of daily life, including work, relationships, confidence and emotional wellbeing. For some women, symptoms are mild and manageable, while for others they can significantly interfere with normal activities.


Understanding symptom patterns and receiving appropriate treatment can help improve quality of life. With a personalised management plan, many women achieve good symptom control and feel more in control of their menstrual cycle and overall wellbeing.

When to See a Specialist

You should consider specialist assessment if:

  • Premenstrual symptoms interfere with work, relationships or daily life

  • Mood changes feel overwhelming or unpredictable

  • Symptoms are becoming more severe over time

  • You suspect you may have PMDD

  • Standard treatments have not improved symptoms


If you experience severe depression or suicidal thoughts, urgent medical support should be sought immediately.

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